INNATE IMMUNE SYSTEM RECEPTORS
What are innate immune system receptors called?
Pattern recognition receptors
What do they recognise?
PAMPS: Pathogen Associated Molecular Patterns
Where can they be found?
1. Bound to the cell membranes
2. Inside the cell itself: cytoplasm
3. Extracellularly: in the serum
What can they recognise?
1. Bacteria
2. Viruses
3. Fungi
What can be used to recognise?
LRR: Leucine Rich Repeats
What effect can they cause?
1. Activation of gene transcription
2. Phagocytosis
3. Cytokine secretion
4. Complement activation
and this all, is INFLAMMATION
